Journal of Mid-life Health Journal of Mid-life Health
Home | About us | Editorial board | Search | Ahead of print | Current Issue | Past Issues | Instructions | Online submission | Subscribe | Advertise Users Online: 369  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size 


REVIEW ARTICLE
Year : 2013  |  Volume : 4  |  Issue : 3  |  Page : 140-146

The role of oxidative stress in menopause


Department of Andrology, Center for Reproductive Medicine, Cleveland Clinic, Cleveland, Ohio, USA

Correspondence Address:
Ashok Agarwal
Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195
USA
Login to access the Email id

Source of Support: Support is from the Center for Reproductive Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Conflict of Interest: None


DOI: 10.4103/0976-7800.118990

Rights and Permissions

This review will discuss the concept of reproductive aging, which includes the definition of menopause, its symptoms, and predisposing conditions. It will elaborate upon the contributory factors implicated in the pathogenesis of menopause, focusing most prominently on oxidative stress. Specifically, this paper will explain how oxidative stress, in the form of free radicals and antioxidant deficiencies, has been directly linked to the decline of estrogen during reproductive aging. Additionally, this paper will elaborate upon the treatment options aimed at mitigating the menopausal symptoms and hormonal deficiencies that can lead to various disease processes. Treatment options such as hormonal therapy, antioxidant supplementation, and lifestyle modification have been explored for their effectiveness in treating and preventing the symptoms and sequelae of menopause. The majority of information in this review was obtained through PubMed and the National Library of Medicine. While most references in this paper are original research articles, a limited number of references are comprehensive reviews on the topic.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed5737    
    Printed148    
    Emailed0    
    PDF Downloaded1172    
    Comments [Add]    
    Cited by others 6    

Recommend this journal