|Year : 2019 | Volume
| Issue : 4 | Page : 184-191
The role of lifestyle in developing and maintaining vasomotor symptoms: A cross-sectional study among Iranian postmenopausal women
Mozhgan Hashemzadeh1, Afsaneh Keramat2, Leila Mollaahmadi1, Ashraf Ghiasi1, Arezoo Haseli3
1 Student Research Committee, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Ilam, Iran
2 Reproductive Studies and Women's Health Research Center, Shahroud University of Medical Sciences, Shahroud, Iran
3 Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran
|Date of Web Publication||26-Dec-2019|
Ms. Arezoo Haseli
Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam
Source of Support: None, Conflict of Interest: None
| Abstract|| |
Objective: Lifestyle patterns are not only related to healthy life but also could be related to modifying menopausal symptoms. Considering the lack of data, the present study aimed to evaluate the relationship between lifestyle and vasomotor symptoms among Iranian postmenopausal women. Materials and Methods: The present cross-sectional questionnaire-based study was conducted among 302 eligible postmenopausal women referring to Shahroud health centers (Shahroud, Iran) during June 2017 and October 2018. The Iranian standard questionnaire on women health project (Saba questionnaire) was used for data collection. Our data were analyzed using the SPSS software (version 18). Descriptive statistics, Chi-square test, Fisher's exact test, and multiple logistic regression were used to address sociodemographic characteristics among our participants and the relations between lifestyle and vasomotor symptoms. Results: We found a significant relation between daily dairy units (P = 0.05), daily vegetable units (P = 0.01), weekly use of solid oils (0.01), and hot flush. The relation between daily vegetable units and urinary incontinence was also statistically significant (P = 0.02). When we use multiple logistic regression, we found significant predictive relations between daily vegetable unit status (P = 0.01), weekly use of solid oils (P = 0.04), body mass index (P = 0.03), and hot flush. Conclusion: The study provided findings to support the probable relation between some of lifestyle-related variables and vasomotor symptoms in postmenopausal women.
Keywords: Climacteric, hot flashes, lifestyle, menopause, urinary incontinence
|How to cite this article:|
Hashemzadeh M, Keramat A, Mollaahmadi L, Ghiasi A, Haseli A. The role of lifestyle in developing and maintaining vasomotor symptoms: A cross-sectional study among Iranian postmenopausal women. J Mid-life Health 2019;10:184-91
|How to cite this URL:|
Hashemzadeh M, Keramat A, Mollaahmadi L, Ghiasi A, Haseli A. The role of lifestyle in developing and maintaining vasomotor symptoms: A cross-sectional study among Iranian postmenopausal women. J Mid-life Health [serial online] 2019 [cited 2023 Feb 2];10:184-91. Available from: https://www.jmidlifehealth.org/text.asp?2019/10/4/184/274013
| Introduction|| |
Menopause is a normal physiologic period and also an important stage of an individual's life. It is not only related to the end of reproductive cycles but also confronts women with a variation of vasomotor, physical, and sexual problems. The age at initiation of menopause has been estimated between 44.6 and 52 years, but it could vary worldwide. Iranian women often experience natural menopause between the ages of 48.66 and 50.4 in different regions.
Hormonal replacement therapy is a well-known treatment for vasomotor symptoms. It also confronts women with various advantages and disadvantages which impact on women's decision-making. Hence, most of them decide to adopt themselves with this condition. Vasomotor and other menopausal symptoms cause considerable impact on health-related quality of life among this population.
Moreover, women who experience menopause at earlier ages are predisposed to develop cardiovascular diseases. Furthermore, current evidence support the relationship between coronary heart disease, heart failure, stroke, and natural menopause in younger ages. The impact of menopause as a risk factor in presenting life-threatening diseases, highlights the importance of considering preventive strategies in this population; therefore, it is critical to monitor lifestyle pattern among this population to prevent menopausal symptoms as well as further physical problems. Previous studies showed controversies regarding the relation between lifestyle and vasomotor symptoms that emerge the need for further observations.
Given the lack of adequate data on the relation between lifestyle and menopausal vasomotor symptoms, the present study was conducted to demonstrate an overview on postmenopausal women lifestyle in Iran and also the relations between lifestyle and menopausal symptoms among this population. We hypothesized that monitoring lifestyle could be an effective method in modifying menopausal symptoms.
| Materials and Methods|| |
The present cross-sectional study was conducted between June 2017 and October 2018. The study protocol was in compliance with the Declaration of Helsinki and ethical considerations of ethics committee of Shahroud University of Medical Sciences and this committee approved the study protocol (approval No: IR.SHMU.REC.1395.154). All postmenopausal women referring to Shahroud health centers were invited to participate in the study after receiving adequate information on the study aims. Included participants aged 40–55, had no hormone replacement therapy during the past 6 months, and no history of oophorectomy. They all had their last menstruation within 3 years ago. As hot flashes often stop occurring after a year or 2 years of menstrual interruption.
Shahroud city has 10 urban health centers and among them, we selected three referral centers including: Azima health center, 12th Farvardin health center, and Mahdi Abad health center. Our reason for selecting these centers was the considerable number of clients in these centers in Shahroud.
Considering the total population of menopause women in Shahroud, Iran (n = 15782) and the prevalence of menopausal symptoms (75%), our sample size was calculated as 283 women using OpenEpi software (version 3.0, open-source calculator, SSPropor, www. OpenEpi.com). As hot flashes often stop occurring after a year or 2 years of menstrual interruption, all participants had their last menstruation within 3 years ago. Volunteer women who met following inclusion criteria: women aged 40–55 years, no history of oophorectomy, and the absence of hormone replacement therapy during 6 months before the study participation enrolled in the study and provided written informed consent. Totally, 302 postmenopausal women participated in the study based on convenience sampling method (138 participants were selected from Azima health center, 99 women were selected from 12th Farvardin health center, and 65 eligible postmenopausal women were selected from Mahdi Abad health center). We used the standard questionnaire on women health project (Saba questionnaire) which was developed and approved by the Iran Ministry of Health and was commonly used in health centers to address women characteristics in three different sections: first section included questions on sociodemographic characteristics (age, education, occupation, body mass index (BMI), number of children, and date of last menstrual period), second part was related to data on women life-style during the last year and contained three subsection on nutrition (specific diet, food groups serving per day and food habits); physical activity (including type and duration of activities per day and per week) and tobacco use, and finally, the third section was providing the data on menopause variables and symptoms (date of menopause, menarche age, age at the time of first delivery, number of pregnancy, number of delivery, hot flush, night sweat, vaginal dryness, and urinary incontinence). Completing the questionnaire took an average of 12 min and participants did not receive any incentives for participation. The Statistical package for the social sciences version 18.0 (SPSS Inc, Chicago, IL, USA) was used for data analysis. We used descriptive statistics as well as Chi-square test, Fisher's exact test, and multiple logistic regression to categorize sociodemographic characteristics and the relations between lifestyle of participants and vasomotor symptoms.
| Results|| |
Totally, 371 women were invited to participate in the study and 28 women were not volunteered and 41 women were not eligible; finally, 302 menopaused women completed participation. The mean and standard deviation of age in our study was 49.74 ± 3.88 years and mean age of menopause among our participants was 48.76 ± 3.87. The majority of women (44.7%) had elementary education and the most prevalent menopausal symptom in our study was hot flush (55.60%). Other sociodemographic and menopausal symptoms are addressed in [Table 1]. Among sociodemographic variables, we found significant relationship between marital status and urinary incontinence (P = 0.05), BMI and hot flush (P = 0.04), age and vaginal dryness (P = 0.04) as well as menopausal age and vaginal dryness (P = 0.04).
|Table 1: Sociodemographic characteristics and menopause symptoms of participants|
Click here to view
We also assessed daily and weekly nutritional habits among our participants, as well as physical activities and tobacco or alcohol consumption. The majority of our participants reported weekly use of solid oils (65.20%). In addition to the type of physical activities, we also addressed severity, days of activity per week, daily and weekly duration of activities among our participants and based on these characteristics, we categorized our participants into two groups who had satisfactory or unsatisfactory physical activity. Most of the participants who had weekly regular walking, reported mild severity (35.90%), and mean weekly duration of 170.92 ± 99.60 min. Among participants who reported working as physical activity, 42 participants (63.60%) had mild activity and mean duration of 828.68 ± 637.30 min/week. Among women who report exercise as physical activity 13 participants (36.10%) had moderate severity of exercise and mean weekly duration of 344.80 ± 478.13 min. None of participants reported alcohol or amphetamine consumption. Other factors relating lifestyle are summarized in [Table 2].
|Table 2: Lifestyle of participants (diet, physical activities, and tobacco/alcohol consumption)|
Click here to view
Chi-square and Fisher's exact test evaluated the relationship between lifestyle and vasomotor symptom among postmenopausal women in our study. Our findings demonstrated a significant relation between daily dairy units status and hot flush (P = 0.05). Chi-square test results also produced a significant relation between daily vegetable units and hot flush (P = 0.01). Women who had regular weekly use of solid oils were more likely to suffer from menopausal hot flush (P = 0.01). Our findings also showed statistically significant (P = 0.02) relation between daily vegetable units status and urinary incontinence [Table 3].
We also used multiple logistic regression and the following variables entered the model: daily dairy unit status, daily vegetable units' status, weekly use of solid oils, and BMI. We found significant predictive relations between daily vegetable units status (P = 0.01), weekly use of solid oils (P = 0.04), BMI (P = 0.03), and hot flush.
| Discussion and Conclusion|| |
The present study designed to demonstrate lifestyle patterns and vasomotor symptoms among Iranian postmenopausal women, as well as the relation between these variables. We found hot flush as the most common symptom among our population that was significantly related to daily dairy and vegetable units, as well as weekly use of solid oils.
Previous studies also mentioned hot flush as the most prevalent and distressing menopausal symptom, which is consistent with our findings. Hot flush is not a life-threatening symptom during menopausal period and therefore has not received adequate attention in previous studies. Estrogen withdrawal is the main physiologic cause of hot flushes. The hot flush episodes could be induced by a variety of triggers such as stressful situations, changes in temperature and smoking as well as alcohol, caffeine or warm drinks consumption. Although the prevalence of tobacco use or alcohol consumption among women is increasing, many Iranian women avoid substance or alcohol use due to cultural context, legal prohibition, alcohol use-related stigma and religious beliefs, which could be an important indicator in reducing hot flush episodes. Our findings also demonstrated no history of alcohol or amphetamine consumption among our participants.
Regular exercise could be another important factor for preventing development of hot flushes or night sweat episodes. Regular aerobic exercises have been suggested as the most effective approach to control hot flush episodes., Walking was the most prevalent physical activity among our participants, but most of our participants had unsatisfactory walking status considering severity of walking, weekly episodes of walking and weekly duration of this activity. Unsatisfactory status of walking among our study population was the probable reason for insignificant relation between walking as physical activity and hot flushes episodes. Functional disabilities and chronic pain in postmenopausal women could be another major reason for avoiding physical activities in this population. Furthermore, due to the lack of estrogen, osteoporosis is a prevalent finding in menopausal women, which is related to chronic pain and higher incidence of bone fracture. Although physical activities are recommended for preventing the progress of osteoporosis, many menopausal women avoid physical activities due to preventing bone damages and the risk of fractures.,
Obesity and overweight are prevalent in postmenopausal women. They are also probable risk factors for presenting hot flushes. Previous studies on the relation between BMI and hot flushes episodes are controversial. In our setting, we found a statistically significant relation between BMI and hot flush. Furthermore, weekly use of solid oils was significantly higher among postmenopausal women with hot flush experiences, which was probably due to cultural beliefs and attitudes regarding benefits of solid oils consumption among this population in our country or higher prevalence of using solid oils among overweight people.
One prospective cohort study on 10,787 postmenopausal women showed a significant relationship between night sweat and increased risk of coronary heart diseases. Although our research was not designed to address this possible relationship, the total prevalence of night sweat in our population was more than other studies, that might be attributed to the factors influencing presence of vasomotor symptoms such as climate situation, lifestyle patterns, and the way of confronting with the end of reproductive life among women. The prevalence of night sweat in our participants was closer to the percentages reported in Iranian studies.,
One of the limitations in our study was related to not using biochemical tests to confirm menopause, and hence, menopausal age was self-reported in our study. Furthermore, we did not address the status of using nonprescription remedies by our participants (such as vitamin E, herbal, and complementary medicine supplements and methods); hence, the impact of these remedies has not been proven in previous clinical trials.
Lifestyle patterns and balanced nutritional diet have been noted effective in minimizing menopausal symptoms, but this relationship has received little attention in previous studies investigating postmenopausal life in Iran. The study provided an overview on components relating lifestyle among Iranian postmenopausal women which was missing in previous studies, we also addressed the relationship between lifestyle-related variables and menopausal symptoms among postmenopausal women as well as valuable guidance for further investigations in this population. We showed significant relation between daily dairy and vegetable units and hot flush, as the most prevalent menopausal symptom. Although dietary supplements are not commonly used by menopausal women for controlling menopausal symptoms, especially among low socioeconomic populations, we recommend further clinical trials to address the impacts of dietary supplements on pre- and postmenopausal symptoms.
The present study was supported by Shahroud University of medical sciences. We hereby acknowledge the research deputy for grant No 940277.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Al Dughaither A, AlMutairy H, AlAteeq M. Menopausal symptoms and quality of life among Saudi women visiting primary care clinics in Riyadh, Saudi Arabia. Int J Womens Health 2015;7:645-53.
Golshiri P, Akbari M, Abdollahzadeh MR. Age at natural menopause and related factors in Isfahan, Iran. J Menopausal Med 2016;22:87-93.
Manson JE, Ames JM, Shapiro M, Gass ML, Shifren JL, Stuenkel CA, et al.
Algorithm and mobile app for menopausal symptom management and hormonal/non-hormonal therapy decision making: A clinical decision-support tool from the North American Menopause Society. Menopause 2015;22:247-53.
Liu K, He L, Tang X, Wang J, Li N, Wu Y, et al.
Relationship between menopause and health-related quality of life in middle-aged Chinese women: A cross-sectional study. BMC Womens Health 2014;14:7.
Tiznobaik A, Taheri S, Momenimovahed Z, Kazemnejad A, Mirmolaei ST. Effects of counseling on lifestyle of menopause women and their spouses: A randomized, controlled trial study (RCT). J Gen Med 2018;15:99-103.
Gold EB, Block G, Crawford S, Lachance L, FitzGerald G, Miracle H, et al.
Lifestyle and demographic factors in relation to vasomotor symptoms: Baseline results from the study of women's health across the nation. Am J Epidemiol 2004;159:1189-99.
Berek JS, Novak E. Berek & Novak's Gynecology. Philadelphia: Lippincott Williams & Wilkins; 2012.
Daley A, MacArthur C, Mutrie N, Stokes-Lampard H. Exercise for vasomotor menopausal symptoms. Cochrane Database Syst Rev 2007;4:CD006108.
Utian WH. Psychosocial and socioeconomic burden of vasomotor symptoms in menopause: A comprehensive review. Health Qual Life Outcomes 2005;3:47.
Sturdee DW, Hunter MS, Maki PM, Gupta P, Sassarini J, Stevenson JC, et al.
The menopausal hot flush: A review. Climacteric 2017;20:296-305.
Slade T, Chapman C, Swift W, Keyes K, Tonks Z, Teesson M. Birth cohort trends in the global epidemiology of alcohol use and alcohol-related harms in men and women: Systematic review and metaregression. BMJ Open 2016;6:e011827.
Abbasi-Ghahramanloo A, Fotouhi A, Zeraati H, Rahimi-Movaghar A. Prescription drugs, alcohol, and illicit substance use and their correlations among medical sciences students in Iran. Int J High Risk Behav Addict 2015;4:e21945.
Daley AJ, Thomas A, Roalfe AK, Stokes-Lampard H, Coleman S, Rees M, et al.
The effectiveness of exercise as treatment for vasomotor menopausal symptoms: Randomised controlled trial. BJOG 2015;122:565-75.
North American Menopause Society. Treatment of menopause-associated vasomotor symptoms: Position statement of the North American Menopause Society. Menopause 2004;11:11-33.
Küçükçakır N, Altan L, Korkmaz N. Effects of pilates exercises on pain, functional status and quality of life in women with postmenopausal osteoporosis. J Bodyw Mov Ther 2013;17:204-11.
Subashi B, Butt DS, Kamberi F, Sinanaj G, Bilushi Y. Physical activity recommended for osteoporosis. Prevention 2017;3.
Shobeiri F, Jenabi E, Poorolajal J, Hazavehei SM. The association between body mass index and hot flash in midlife women: A meta-analysis. J Menopausal Med 2016;22:14-9.
Gast GC, Pop VJ, Samsioe GN, Grobbee DE, Nilsson PM, Keyzer JJ, et al.
Vasomotor menopausal symptoms are associated with increased risk of coronary heart disease. Menopause 2011;18:146-51.
Islam MR, Gartoulla P, Bell RJ, Fradkin P, Davis SR. Prevalence of menopausal symptoms in Asian midlife women: A systematic review. Climacteric 2015;18:157-76.
Sussman M, Trocio J, Best C, Mirkin S, Bushmakin AG, Yood R, et al.
Prevalence of menopausal symptoms among mid-life women: Findings from electronic medical records. BMC Womens Health 2015;15:58.
Freeman EW, Sherif K. Prevalence of hot flushes and night sweats around the world: A systematic review. Climacteric 2007;10:197-214.
Masoumi M, Azizi M, Atarod Z, Gartoulla P, Abdollahi F, Fooladi E. A systematic review of prevalence of vasomotor and sexual symptoms among Iranian middle-aged women. Red Crescent Medical Journal 19:[e43952]. Doi://doi.org/10.5812/ircmj.43952.
Asadi M, Jouyandeh Z, Nayebzadeh F. Prevalence of menopause symptoms among Iranian women. J Fam Reprod Health 2012;6:1-3.
Mehta N. Managing your own menopause. Int J Curr Trends Sci Technol 2017;7:20374-7.
[Table 1], [Table 2], [Table 3]